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Research Projects

The CREATElab offer a number of research projects designed for students, and can be tailored for undergraduate, honours or post-graduate levels of study. Postdoctoral research fellowships are also available through CREATElab.


Research projects in the CREATElab focus primarily on mechanical circulatory and respiratory support systems including ventricular assist devices (VADs) and extracorporeal membrane oxygenation (ECMO). Prototype development is completed on site using a range of 3D printers, moulding facilities and mechanical workshop, while complex manufacturing is completed through the extensive resources of Monash University. Prototype evaluation is also completed on site using numerical simulations (computational fluid dynamics, finite element analysis, lumped parameter models), in-vitro test rigs (mock circulation loops, blood circulation loops), and in-vivo using an in-house facility available through AMREP. 

​Commercial services are also available through the CREATElab. Please contact us if you would like more information.

Recent publications

Current and future strategies to monitor and manage coagulation in ECMO patients

Saeedreza Zeibi Shirejini, Josie Carberry, Zoe K McQuilten, Aidan JC Burrell, Shaun D Gregory, Christoph E Hagemeyer

Thrombosis Journal 21 (1), 1-20, 2023


Estimation of Left Ventricular Stroke Work for Rotary Left Ventricular Assist Devices.

EL Eric L Wu, Martin Maw, Andrew F Stephens, Michael C Stevens, John F Fraser, Geoffrey Tansley, Francesco Moscato, Shaun D Gregory

ASAIO Journal (American Society for Artificial Internal Organs: 1992), 2023

Hybrid laser powder bed fusion and hot isostatic pressing of Ti-6Al-4V parts without degassing for process efficiency

L Zeng, WH Kan, K Zhang, CVS Lim, LNS Chiu, SD Gregory, A Huang

Journal of Manufacturing Processes 92, 63-74, 2023


The effect of drainage cannula tip position on risk of thrombosis during venoarterial extracorporeal membrane oxygenation

Avishka Wickramarachchi, Mehrdad Khamooshi, Aidan Burrell, Vincent A Pellegrino, David M Kaye, Shaun D Gregory

Computer Methods and Programs in Biomedicine 231, 107407, 2023


The effect of arterial cannula tip position on differential hypoxemia during venoarterial extracorporeal membrane oxygenation

Avishka Wickramarachchi, Aidan JC Burrell, Andrew F Stephens, Michael Šeman, Ashkan Vatani, Mehrdad Khamooshi, Jaishankar Raman, Rinaldo Bellomo, Shaun D Gregory

Physical and Engineering Sciences in Medicine 46 (1), 119-129, 2023


Impact of Concomitant Mitral Regurgitation on the Hemodynamic Indicators of Aortic Stenosis

Michael Šeman, Andrew F Stephens, Antony Walton, Stephen J Duffy, David McGiffin, Shane Nanayakkara, David M Kaye, Shaun D Gregory, Dion Stu

Journal of the American Heart Association 12 (4), e025648, 2023

Comparison of single-stage and multi-stage drainage cannula flow characteristics during venoarterial extracorporeal membrane oxygenation

A Wickramarachchi, SD Gregory, M Khamooshi

Physics of Fluids 35 (2), 2023


A computational fluid dynamics assessment of 3D printed ventilator splitters and restrictors for differential multi-patient ventilation

DJ Duke, AL Clarke, AL Stephens, L Djumas, SD Gregory

3D Printing in Medicine 8 (1), 1-14, 2022


Improved Flow Dynamics of Extracorporeal Membrane Oxygenation via Design Modification of Dual-Lumen Cannulas

M Azimi, S Liao, A Vatani, A Burrell, SD Gregory

ASAIO Journal 68 (11), 1358-1366, 2022


Tissue-Mimicking Materials for Ultrasound-Guided Needle Intervention Phantoms: A Comprehensive Review

SA Armstrong, R Jafary, JS Forsythe, SD Gregory

Ultrasound in Medicine & Biology, 2022


Clinician Perspectives on Cannulation for Extracorporeal Cardiopulmonary Resuscitation: A Mixed Methods Analysis

D Wanigasekara, VA Pellegrino, AJC Burrell, N Aung, SD Gregory

ASAIO Journal, 10.1097, 2022


Development and validation of non-invasive endothelial shear stress (ESS) estimations of coronary artery haemodynamics using computational modelling

J Chan, KY Thum, A Comella, E Kalman, J Carberry, S Gregory, J Cameron, A Brown

European Heart Journal 43 (Supplement_2), ehac544. 1197, 2022


In silico Prediction of Thrombosis Risk in a Ventricular Assist Device Supported Right Heart: The Impact of Cannulation Site

KY Thum, S Liao, J Carberry, D McGiffin, SD Gregory

ASAIO Journal 68 (10), 1263-1271, 2022


Fabrication and characterization of tissue-mimicking phantoms for ultrasound-guided cannulation training

R Jafary, S Armstrong, T Byrne, A Stephens, V Pellegrino, SD Gregory

ASAIO Journal 68 (7), 940-948, 2022


Ex vivo evaluation of personal protective equipment in hands-on defibrillation

Andrew F Stephens, Michael Šeman, Ziad Nehme, Aleksandr Voskoboinik, Karen Smith, Shaun D Gregory, Dion Stub

Resuscitation Plus 11, 100284, 2022

Hemodynamics of small arterial return cannulae for venoarterial extracorporeal membrane oxygenation

Andrew F Stephens, Avishka Wickramarachchi, Aidan JC Burrell, Rinaldo Bellomo, Jaishankar Raman, Shaun D Gregory

Artificial organs 46 (6), 1068-1076, 2022


Computational assessment of the nasal air conditioning and paranasal sinus ventilation from nasal assisted breathing therapy

M Khamooshi, DF Fletcher, H Salati, S Vahaji, S Gregory, K Inthavong

Physics of Fluids 34 (5), 051912, 2022


Validation of Non-Invasive Endothelial Shear Stress (ESS) Estimations of Coronary Artery Haemodynamics via In-Silico and In-Vivo Modelling

J Chan, K Thum, A Ihdayhid, A Comella, J Cameron, M Khamooshi, U Thakur, S Nicholls, J Carberry, S Gregory, A Brown, E Kalman

Heart, Lung and Circulation 31, S188, 2022

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